This systematic review used meta-ethnographic synthesis to explore patients’ and healthcare professionals’ views on, and experiences with, error disclosure. The 15 included studies highlighted a misalignment in attitudes and expectations between patients and healthcare professionals regarding error disclosure. While patients and family members emphasized the importance of disclosure with sincere regret and actions to prevent future errors, healthcare professionals cited several barriers to disclosure (e.g., blame culture, avoidance of litigation, lack of disclosure training and guidance).