Diagnostic error is common in the primary care setting, with a recent study estimating that 5% of adults in the United States experience a diagnostic error each year. Missed and delayed diagnoses of cancer are a major source of diagnostic error in primary care and account for a large proportion of malpractice lawsuits. This study used detailed, video-based clinical vignettes to analyze how primary care physicians in the United Kingdom chose to initiate the diagnostic workup for lung cancer in patients presenting with a variety of symptoms. The investigators found that clinicians did not consistently pursue further testing in patients with high-risk symptoms, particularly when they failed to elicit additional information from the patient. A recent study found that electronic triggers increased the rate of appropriate workup in patients with suspected cancer, indicating the potential for decision support systems to reduce diagnostic error.