The National Quality Forum used expert consensus and evidence review to identify 30 health care “safe practices” that should be consistently utilized to minimize the risk of harm to patients. Originally disseminated in 2003 and updated in 2006, these practices are organized into seven primary content areas: creating a culture of safety, matching health care needs with service delivery capability, facilitating information transfer and clear communication, preventing healthcare-associated infections, honoring patient wishes for informed content and disclosure, increasing safe medication use, and adopting safe practices in specific clinical care settings or for specific processes of care. Each practice is presented in capsule form with detailed specifications, applicable setting of care, supporting evidence, and additional background.