Healthcare organizations use trigger tools to identify potential errors or adverse events in the electronic health record (EHR), measure the frequency of errors, and track safety improvements. Three hospitals in Germany conducted a feasibility study of implementing the Institute for Healthcare Improvement (IHI) Global Trigger Tool (GTT) in two general surgery units and one neurosurgery unit. Twenty-two feasibility criteria were developed (low-, moderate-, problematic-level of challenge) which may help guide successful implementation of the GTT.