Trends in medical and nonmedical use of prescription opioids among US adolescents: 1976–2015.
Opioid use is a patient safety epidemic. This survey of high school seniors in the United States found that prescription opioid use usually precedes nonmedical opioid use, suggesting that improving prescribing practices in accordance with the recent Centers for Disease Control and Prevention guideline is important to address medical and nonmedical opioid use.