Medication reconciliation has the potential to reduce medication errors during transitions of care. This study used educational and electronic health record-based interventions to increase completed medication reconciliation in one health systems’ pediatric emergency department (ED) and urgent care (UC) settings. Post-implementation, completed medication reconciliation in UCs increased from 25% to 82% within four months; in the pediatric ED, completed reviews increased from 26% to 64% within 18 months.