Measuring safety culture is viewed as a best practice and is endorsed by the Leapfrog Group and the Agency for Healthcare Research and Quality (AHRQ). However, studies have not consistently demonstrated a direct relationship between safety culture and improved patient outcomes. In this observational cohort study, researchers analyzed data from 19,357 discharges for acute myocardial infarction (AMI) across 171 hospitals and associated data from AHRQ Hospital Survey on Patient Safety Culture surveys between 2008 and 2013. They found no association between 30-day AMI mortality and safety culture scores. A recent PSNet interview with Mary Dixon-Woods discussed the evolving concept of safety culture.