Overriding drug-drug interaction alerts in clinical decision support systems: a scoping review.
Computerized decision support systems can alert clinicians to drug-drug interactions (DDIs), but the alert fatigue contributes to alert overrides. This scoping review includes 34 studies from the United States and international settings and identified a high prevalence of DDI alert overrides. The authors discuss the need for improved decision support systems to improve DDI alerts and actionable metrics to measure harms associated with alert overrides.