This retrospective study, conducted in a children's hospital with a widely used commercial computerized provider order entry (CPOE) system, used active surveillance to examine the frequency and types of medication errors associated with CPOE. The authors found an overall rate of medication errors of 53.9 per 1000 patient-days, similar to a prior study; only 19% of these were deemed to be related to design features of the CPOE system. These included errors in selecting medications from drop-down menus and selecting incorrect order sets. None of the CPOE-related adverse drug events (ADEs) resulted in patient injury. While prior research has raised concern that implementation of CPOE systems may result in more ADEs, other research supports this study's conclusion that careful attention to CPOE design features may ameliorate the risk of ADEs.