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Study

Major congenital malformations after first-trimester exposure to ACE inhibitors.

Cooper WO, Hernandez-Diaz S, Arbogast PG, et al. Major Congenital Malformations after First-Trimester Exposure to ACE Inhibitors. New England Journal of Medicine. 2006;354(23). doi:10.1056/nejmoa055202.

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February 17, 2011
Cooper WO, Hernandez-Diaz S, Arbogast PG, et al. New England Journal of Medicine. 2006;354(23).
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This U.S. Food and Drug Administration (FDA)– and AHRQ–funded study documents the possibility of adverse effects on the fetus when mothers take angiotensin-converting enzyme (ACE) inhibitors during the first trimester of pregnancy.
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Cooper WO, Hernandez-Diaz S, Arbogast PG, et al. Major Congenital Malformations after First-Trimester Exposure to ACE Inhibitors. New England Journal of Medicine. 2006;354(23). doi:10.1056/nejmoa055202.