Standardized handoffs are known to improve patient outcomes in many clinical settings. This review analyzed research on standardized handoffs in acute care surgery, which includes trauma, emergency general surgery, and surgical critical care. Ten studies were identified but the heterogeneity of outcomes made it difficult to compare the various studies. Based on the review, the authors conditionally recommend use of a standardized handoff in perioperative interactions, between emergency medical services and trauma team, and between wards and intensive care units.