This commentary discusses the development of an Intensive Care Unit Safety Reporting System (ICUSRS), an endeavor funded by AHRQ. The authors outline the context for improved reporting systems in intensive care units (ICUs), current challenges, and the benefits of a web-based platform. They discuss how reports are generated, collected, and ultimately disseminated back to frontline staff using the system. They report on the system's early success in 18 ICUs and express their commitment to expanding the application of this tool to improve patient safety.