Active and engaged leadership can improve safety culture and organizational performance on measures of safety and quality. However, prior studies have consistently shown that management has an overly rosy view of safety culture compared to frontline workers, perhaps limiting the ability of managers to improve safety. This study reports on a teamwork training based intervention for a multidisciplinary group of hospital managers. The training emphasized leadership behaviors known to influence safety culture, such as encouraging open discussion of safety issues and errors, and resulted in improved attitudes and use of the targeted leadership behaviors. The importance of leadership in creating a positive safety culture was highlighted in a 2017 Joint Commission Sentinel Event Alert.