This resource represents a collection of special articles published in the Joint Commission Journal on Quality and Safety between September 2002 and November 2003. The nine-volume series builds on the concept of microsystems, defined as the functional frontline units that deliver care to patients, and how achieving success at this level stimulates wider organizational change. A combination of case studies and compiled learning from 20 high-performing microsystems nationally serve as the platform to provide recommendations for success. Topics covered through the series include leadership, culture, performance improvement, information technology, patient safety, and other related issues.